Peer-Reviewed Publications

  • Raman spectroscopic modality to examine therapeutic efficacy of Galectin-3 inhibitor in prostate cancer. (2026)

    DOI: https://doi.org/10.1016/j.bbrc.2025.151646

    S. Ghazanfarpour*, A. Sheikhsofla*, M. Pourrahimi*, S. Sharma, A. Skomra, A. Sharikova, S. A. Schwartz, S. D. Mahajan, A. Khmaladze, R. Aalinkeel
    Biochemical and Biophysical Research Communications

  • Molecular signatures of neuro-HIV and methamphetamine co-morbidity revealed by Raman spectroscopy in postmortem human brain tissue. (2026)

    DOI: https://doi.org/10.1016/j.brainres.2025.150036

    S. Ghazanfarpour*, R. K. Das, K. W. Cheung, E. Zabel, M. Pourrahimi*, R. Aalinkeel, A. Sharikova, A. Khmaladze, S. D. Mahajan
    Brain Research

  • Utilizing Machine Learning for Raman Spectral Data Analysis of Brain Tissue. (2026)

    DOI: https://doi.org/10.37394/23208.2026.23.6

    S. Ghazanfarpour*, S. Ghazanfarpour*, M. Pourrahimi*, R. K. Das, A. Sharikova, T. Ignatowski, V. P. Muthaiah, S. D. Mahajan, A. Khmaladze
    WSEAS TRANSACTIONS on BIOLOGY and BIOMEDICINE

  • Cryoelectrospun elastin-alginate scaffolds as potential cell delivery vehicles for mesenchymal stromal cell therapy. (2025)

    DOI: https://doi.org/10.1038/s41598-025-03822-x

    P. Ramesh*, R. Pena*, J. M. Morrissey, N. Moskwa*, K. Tubbesing, X. Zhang, D. Nelson, J. Castracane, A. Khmaladze, S. T. Sharfstein, M. Larsen, Y. Xie
    Scientific Reports

  • Quantitative phase imaging comparison of digital holographic microscopy and transport of intensity equation phase through simultaneous measurements of live cells. (2023)

    DOI: https://doi.org/10.1016/j.optlaseng.2023.107581

    Carney, Shane & Khoo, Ting Chean & Sheikhsofla, Alireza & Ghazanfarpour, Samaneh & Sharikova, Anna & Mahajan, Supriya & Khmaladze, Alexander & Petruccelli, Jonathan
    Optics and Lasers in Engineering

  • Raman Spectroscopy Based Molecular Signatures of Methamphetamine and HIV Induced Mitochondrial Dysfunction (2022)

    DOI: https://doi.org/10.1016/j.bbrc.2022.06.098

    T. C. Khoo*, R. Aalinkeel, S. Abbasi, S. A. Schwartz, A. Khmaladze, S. D. Mahajan
    (Biochem. and Biophys. Res. Comm.)

  • Raman Microspectroscopy Fingerprinting of Organoid Differentiation State (2022)

    DOI: https://doi.org/10.1186/s11658-022-00347-3

    K. Tubbesing, N. Moskwa*, T. C. Khoo*, D. A. Nelson, A. Sharikova, Y. Feng, M. Larsen, A. Khmaladze
    (Cell. Mol. Biol. Lett.)

  • Automated Quantification of Vomeronasal Glomeruli Number, Size, and Color Composition after Immunofluorescent Staining (2021)

    DOI: https://doi.org/10.1093/chemse/bjab039

    S. J. Bahreini*, J. M. Lin*, F. Etaati, S. Fearnley, J.-F. Cloutier, A. Khmaladze, P. E. Forni
    (Chemical Senses) https://doi.org/10.1093/chemse/bjab039

  • Iron-binding cellular profile of transferrin using label-free Raman hyperspectral imaging and singular value decomposition (SVD) (2021)

    DOI: https://doi.org/10.1016/j.freeradbiomed.2021.04.030

    K. Tubbesing, T. C. Khoo*, S. J. Bahreini*, A. Sharikova, M. Barroso, A. Khmaladze
    (Free Radical Biology and Medicine)

  • Telomere Length Shortening in Microglia: Implication for Accelerated Senescence and Neurocognitive Deficits in HIV (2021)

    DOI: https://doi.org/10.3390/vaccines9070721

    C-B. Hsiao, H. Bedi, R. Gomez, A. Khan, T. Meciszewski, R. Aalinkeel, T. C. Khoo, A. Sharikova, A. Khmaladze, S. D. Mahajan
    (Vaccines) https://doi.org/10.3390/vaccines9070721

  • Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID (2021)

    DOI: https://doi.org/10.1007/s11481-021-10015-6

    E. Clough, J. Inigo, D. Chandra, L. Chaves, J. L. Reynolds, R. Aalinkeel, S. A. Schwartz, A. Khmaladze, S. D. Mahajan
    (J Neuroimmune Pharmacol)

  • Characterization of Nanofibers for Tissue Engineering: Chemical Mapping by Confocal Raman Microscopy (2020)

    DOI: https://doi.org/10.1016/j.saa.2019.117670

    A. Sharikova, Z. I. Foraida*, L. Sfakis, L. Peerzada, M. Larsen, J. Castracane, A. Khmaladze
    (Spectrochimica Acta Part A)

  • Dual wavelength digital holographic imaging of layered structures (2020)

    DOI: https://doi.org/10.1016/j.optcom.2019.124793

    T. C. Khoo*, A. Sharikova, A. Khmaladze
    (Optics Comm.)

  • Comparative phase imaging of live cells by digital holographic microscopy and transport of intensity equation methods (2020)

    DOI: https://doi.org/10.1364/OE.385854

    J. M. Wittkopp*, T. C. Khoo*, S. Carney*, K. Pisila*, S. J. Bahreini*, K. Tubbesing*, S. Mahajan, A. Sharikova, J. Petruccelli, A. Khmaladze
    (Optics Express)

  • Raman Spectroscopy Allows for the Determination of Elephant Ivory Age (2020)

    DOI: https://doi.org/10.1177/0003702820930037

    A. Sharikova, L. Peerzada, K. Pisila*, T. C. Khoo*, A. Cherkinsky, A. Khmaladze
    (Appl. Spectrosc.)

  • Quantitative label-free imaging of iron-bound transferrin in breast cancer cells and tumors (2020)

    DOI: https://doi.org/10.1016/j.redox.2020.101617

    T. C. Khoo*, K. Tubbesing, A. Rudkouskaya, S. Rajoria, A. Sharikova, M. Barroso, A. Khmaladze
    (Redox Biology)

  • Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1 (2020)

    DOI: https://doi.org/10.1016/j.celrep.2020.108255

    J. P. McCauley, M. A. Petroccione, L. Y D’Brant*, G. Todd, N. Affinnih, J. J. Wisnoski, S. Zahid, S. Shree, A. Sousa, R. M. De Guzman, R. Migliore, A. Brazhe, R. D. Leapman, A. Khmaladze, A. Semyanov, D. G. Zuloaga, M. Migliore, A. Scimemi
    (Cell Reports)

  • Methamphetamine-induced apoptosis in glial cells examined under marker-free imaging modalities. (2019)

    DOI: https://doi.org/10.1117/1.JBO.24.4.046503

    L. Y. D’Brant*, H. Desta*, T. C. Khoo*, A. Sharikova, S. D. Mahajan, A. Khmaladze
    J. Biomed. Opt. 24(4), 046503-1 - 046503-10 https://doi.org/10.1117/1.JBO.24.4.046503

  • Mesenchymal Cells Affect Salivary Epithelial Cell Morphology on PGS/PLGA Core/Shell Nanofibers (2018)

    DOI: https://doi.org/10.3390/ijms19041031

    L. Sfakis*, T. Kamaldinov*, A. Khmaladze, Z. F. Hosseini*, D. A. Nelson, M. Larsen, J. Castracane
    (Int. J. Mol. Sci.)

  • Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway (2018)

    DOI: https://doi.org/10.1007/s11481-018-9787-4

    A. Sharikova, E. Quaye, J. Y. Park*, M. C. Maloney*, H. Desta*, R. Thiyagarajan, K. L. Seldeen, N. U Parikh, P. Sandhu, A. Khmaladze, B. R. Troen, S. A. Schwartz, S. D. Mahajan
    (J. Neuroimmune Pharmacology)

Book Chapters

  • Nanofiber characterization by Raman scanning microscopy (2020)

    DOI: http://dx.doi.org/10.1201/9780429340420-10

    A. Khmaladze
    (21st Century Nanoscience: A Handbook), Edited by K. Sattler (Taylor and Francis, 2020)

Full Length Conference Proceedings

  • Assessment of Raman hyperspectral spectra upon depletion of proteins involved in iron transport (2023)

    DOI: https://microbiolab.org/publications.php

    P. Mandal*, A. Sheikhsofla*, S. Ghazanfarpour*, T. C. Khoo*, J. Barra-Carrasco, I. Crousborne, A. Sharikova, A. Khmaladze, M. Barroso
    (Proc. SPIE 12391, 123910L)

  • Quantitative volume comparisons of methamphetamine-induced apoptosis by simultaneous digital holographic microscopy and transport of intensity phase-imaging techniques (2022)

    DOI: https://microbiolab.org/publications.php

    S. Carney*, T. C. Khoo*, K. Tubbesing, A. Sharikova, S. D. Mahajan, J. C. Petruccelli, A. Khmaladze
    (Proc. SPIE 11972, 119720B)

  • The study of cell death mechanisms via simultaneous Raman and transport of intensity phase-imaging techniques (2022)

    DOI: https://microbiolab.org/publications.php

    S. Carney*, T. C. Khoo*, J. Barra-Carrasco, S. Ghazanfarpour*, S. Bahreini*, A. Sharikova, M. Barroso, S. D. Mahajan, J. C. Petruccelli, A. Khmaladze
    (Proc. SPIE 12144, 121440A)

  • Raman mapping of transferrin and ferritin distributions in breast cancer cells (2021)

    DOI: https://microbiolab.org/publications.php

    K. Tubbesing, T. C. Khoo*, A. Sharikova, M. Barroso, A. Khmaladze
    (Proc. SPIE 11655, 1165518)

  • Raman hyperspectral imaging of transferrin-bound iron in T47D and MDA-MB-231 breast cancer cells (2020)

    DOI: https://microbiolab.org/publications.php

    T. C. Khoo*, K. Tubbesing*, A. Rudkouskaya, G. Athanassiadis, A. Sharikova, M. Barroso, A. Khmaladze
    (Proc. SPIE 11251, 112511E-1 - 112511E-6)

  • Detection of the differentiation state of salivary gland organoids for tissue engineering by Raman spectroscopy (2020)

    DOI: https://microbiolab.org/publications.php

    T. C. Khoo*, N. Moskwa*, G. Athanassiadis, A. Sharikova, M. Larsen, A. Khmaladze
    (Proc. SPIE 11251, 1125103-1 - 1125103-7)

  • Measurements of iron-bound transferrin in breast cancer tumor xenografts using Raman spectral imaging (2020)

    DOI: https://microbiolab.org/publications.php

    K. Tubbesing, T. C. Khoo*, A. Rudkouskaya, A. Sharikova, M. Barroso, A. Khmaladze
    (Proc. SPIE 11363, 113630Y-1 - 113630Y-6)

  • Digital holographic microscopy (DHM) and transport of intensity (TIE) phase imaging of live cells (2020)

    DOI: https://microbiolab.org/publications.php

    S. Carney*, T. C. Khoo*, J. Wittkopp*, K. Pisila*, G. Athanassiadis, A. Sharikova, A. Khmaladze, J. Petruccelli
    (Proc. SPIE 11251, 1125122-1 - 1125122-6)

  • Raman hyperspectral imaging of different salivary gland cell types for tissue engineering (2019)

    DOI: https://microbiolab.org/publications.php

    T. C. Khoo*, N. Moskwa*, A. Sharikova, M. Larsen, A. Khmaladze
    (Proc. SPIE 10890, 108901S-1 - 108901S-7)

  • Raman hyperspectral imaging of transferrin-bound iron in cancer cells (2019)

    DOI: https://microbiolab.org/publications.php

    T. C. Khoo*, K. Tubbesing*, C. Pham*, H. Desta*, A. Sharikova, M. Barroso, A. Khmaladze
    (Proc. SPIE 10890, 108901S-1 - 108901S-6)

  • Design of a dual wavelength digital holographic imaging system for the examination of layered structures (2018)

    DOI: https://microbiolab.org/publications.php

    J. C. McFarland*, T. C. Khoo*, A. Sharikova, A. Khmaladze
    (Proc. SPIE 10690, 1069013-1 - 1069013-7)

  • Assessing the age of animal bones and ivories by Raman spectroscopy (2018)

    DOI: https://microbiolab.org/publications.php

    A. Sharikova, L. Peerzada, A. Khmaladze
    (Proc. SPIE 10497, 104971B-1 - 104971B-6)

  • Raman hyperspectral imaging of iron transport across membranes in cells (2016)

    DOI: https://microbiolab.org/publications.php

    A. Das*, F. X. Costa*, A. Khmaladze, M. Barroso, A. Sharikova
    (Proc. SPIE 9976, 99760C-1 - 99760C-6)

  • Digital holographic phase imaging of particles embedded in microscopic structures in three dimensions (2016)

    DOI: https://microbiolab.org/publications.php

    J. Y. Park*, H. Desta*, M. C. Maloney*, A. Sharikova, A. Khmaladze
    (Proc. SPIE 9870, 98700B-1 - 98700B-9)

  • Dual wavelength digital holographic imaging of embedded layered structures (2016)

    DOI: https://microbiolab.org/publications.php

    J. Y. Park*, X. Chen*, A. Sharikova, A. Khmaladze
    (Proc. SPIE 9718, 97182J-1 - 97182J-6)

  • 3D measurements of live cells via digital holographic microscopy and terahertz spectroscopy (2016)

    DOI: https://microbiolab.org/publications.php

    J. Y. Park*, D. Oser*, P. Iapozzuto*, S. Norbury*, S. Mahajan, A. Khmaladze, A. Sharikova
    (Proc. SPIE 9718, 97182D-1 - 97182D-6)

Shorter Conference Proceedings

  • In-line Monitoring of Water Quality by Combined Fluorescence and Raman Spectroscopy. (2017)

    DOI: https://doi.org/10.1364/CLEO_AT.2017.AF2B.5

    Maleev, A. Khan*, L Peerzada, A. Khmaladze, A. Sharikova
    Imaging and Applied Optics 2016, in OSA CLEO, OSA Technical Digest, Optical Society of America

  • Examining live cell cultures during apoptosis by digital holographic phase imaging and Raman spectroscopy (2016)

    DOI: https://doi.org/10.1088/1742-6596/909/1/012001

    A. Khmaladze
    J. Phys.: Conf. Ser. 909, 012001, 1-6 https://doi.org/10.1088/1742-6596/909/1/012001

  • Phase Imaging of Live Central Nervous System Cells during Apoptosis by Digital Holographic Microscopy (2016)

    DOI: https://doi.org/10.1364/3D.2016.JW4A.11

    Y. Park*, M. Maloney*, H. Desta*, S. Mahajan, A. Sharikova, A. Khmaladze
    OSA DH, OSA Technical Digest, Optical Society of America